Featured Collections

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The day humans almost destroyed the world by mistake
Why ancient Rome had better concrete than us.
Why pirates wore eye patches
Why bananas are radioactive

Surprising Facts

10 items•15 min•Public
Ignition and beyond: where the fusion frontier really stands.
Inside the fusion startup boom.
Why fusion power is called the energy of the future.
Could we create a tiny sun on Earth?

Nuclear fusion energy

5 items•17 min•Public
In AI, what’s a “transformer” and how do they work?
Why might superhuman AI kill everyone?
What makes AI sound human?
Can AI be truly creative—or just remixing?

AI

23 items•3h 31m•Public
CRISPR

CRISPR

12 items•56 min•Public
The Monty Hall Paradox: Beating Your Own Intuition
Why are conspiracy theories so sticky?
Myth of the carnivore caveman.
Is mind reading real?

Critical Thinking & Cognitive Bias

9 items•32 min•Public
What is a quantum computing?

Quantum Computing

3 items•11 min•Public

Recent Recordings

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The Radioactive Cereal Prize
▶

The Radioactive Cereal Prize

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Intermediate3 min
Platform vs. Single Asset Biotech Models – John E Milad, Backed By Reality
▶

Platform vs. Single Asset Biotech Models – John E Milad, Backed By Reality

—
Intermediate16 min
Comparing OpenAI and Anthropic Models
▶

Comparing OpenAI and Anthropic Models

—
Intermediate3 min
The Agent That Cowered – John E Milad, Backed By Reality
▶

The Agent That Cowered – John E Milad, Backed By Reality

—
18 min
Activation Energy – John E Milad, Backed By Reality
▶

Activation Energy – John E Milad, Backed By Reality

—
Intermediate20 min

All Recordings

100
⌘K
The Radioactive Cereal Prize

The Radioactive Cereal Prize

Public
—•CultureHistory•Intermediate•3 min
Platform vs. Single Asset Biotech Models – John E Milad, Backed By Reality

Platform vs. Single Asset Biotech Models – John E Milad, Backed By Reality

Public
—•Intermediate•16 min
Comparing OpenAI and Anthropic Models

Comparing OpenAI and Anthropic Models

Public
—•Intermediate•3 min
The Agent That Cowered – John E Milad, Backed By Reality

The Agent That Cowered – John E Milad, Backed By Reality

Public
—•TechnologyBusiness•18 min
Activation Energy – John E Milad, Backed By Reality

Activation Energy – John E Milad, Backed By Reality

Public
—•Technology•Intermediate•20 min
Journey to the Giants: Human Feasibility

Journey to the Giants: Human Feasibility

Public
—•ScienceTechnology•Intermediate•5 min
Mars Missions: Current Plans and Prospects

Mars Missions: Current Plans and Prospects

Public
—•ScienceTechnology•Intermediate•5 min
Future Luxury: Space Hotels Await

Future Luxury: Space Hotels Await

Public
—•BusinessTechnology•Intermediate•4 min
The Model Is Not the Moat:  The Great Bifurcation (Part 3 of 3)

The Model Is Not the Moat: The Great Bifurcation (Part 3 of 3)

Public
—•BusinessTechnology•Intermediate•7 min
The Model Is Not the Moat: Distribution, Regulation & Open-Source Mirage (Part 2 of 3)

The Model Is Not the Moat: Distribution, Regulation & Open-Source Mirage (Part 2 of 3)

Public
—•BusinessTechnology•Intermediate•10 min
The Model Is Not the Moat: Rhetoric vs. Reality in AI’s New Era (Part 1 of 3)

The Model Is Not the Moat: Rhetoric vs. Reality in AI’s New Era (Part 1 of 3)

Public
—•BusinessTechnology•Intermediate•9 min
AI's Transformative Impact Unveiled

AI's Transformative Impact Unveiled

Public
—•BusinessTechnology•7 min
Blood Test Predicts Alzheimer’s Onset

Blood Test Predicts Alzheimer’s Onset

Public
—•Health•Intermediate•5 min
AAV9 Gene Therapy for GM1: Early Signals of from Phase 1/2 results

AAV9 Gene Therapy for GM1: Early Signals of from Phase 1/2 results

Public
—•Intermediate•1 min
Why do cats purr?

Why do cats purr?

Public
—•Science•Intermediate•5 min
Why do we have a tickle response? What is the evolutionary purpose?

Why do we have a tickle response? What is the evolutionary purpose?

Public
—•Science•Intermediate•5 min
How much sleep does a banker need?

How much sleep does a banker need?

Public
—•BusinessCulture•1 min
Something Big Is Happening

Something Big Is Happening

Public
—•BusinessCultureTechnology•27 min
Correlation between intelligence and social conservatism.

Correlation between intelligence and social conservatism.

Public
—•Beginner•4 min
Graham’s Number

Graham’s Number

Public
—•Science•Beginner•3 min
Illich’s Law: When More Is Too Much

Illich’s Law: When More Is Too Much

Public
—•Intermediate•4 min
Rockets Are Too Slow: Why the Future of Space Travel Is Electric and Nuclear

Rockets Are Too Slow: Why the Future of Space Travel Is Electric and Nuclear

Public
—•TechnologyScience•Intermediate•6 min
Cogitative Bias: 'The Curse of Knowledge'

Cogitative Bias: 'The Curse of Knowledge'

Public
—•Intermediate•4 min
SETI@home: How Millions Searched for Alien Life

SETI@home: How Millions Searched for Alien Life

Public
—•TechnologyScience•Intermediate•5 min
Explain Bayes Theorem and its practical applications

Explain Bayes Theorem and its practical applications

Public
—•Beginner•56 sec
Explain Bayes Theorem and its practical applications

Explain Bayes Theorem and its practical applications

Public
—•Intermediate•5 min
Highlights and takeaways from the JP Morgan 2026 healthcare conference

Highlights and takeaways from the JP Morgan 2026 healthcare conference

Public
—•BusinessHealth•Intermediate•4 min
Understanding the 'optimal stopping rule' (aka the Secretary Problem)

Understanding the 'optimal stopping rule' (aka the Secretary Problem)

Public
—•Fun•Intermediate•5 min
NVIDIA and Lilly re-engineering drug discovery loops

NVIDIA and Lilly re-engineering drug discovery loops

Public
—•BusinessHealthTechnology•Intermediate•11 min
Tell me about HRV (heart rate variability) and its impact on health and well being. (Remix)

Tell me about HRV (heart rate variability) and its impact on health and well being. (Remix)

Public
—•Health•10 min
Tell me about HRV (heart rate variability) and its impact on health and well being.

Tell me about HRV (heart rate variability) and its impact on health and well being.

Public
—•Health•Intermediate•8 min
Tell me about HRV (heart rate variability) and its impact on health and well being.

Tell me about HRV (heart rate variability) and its impact on health and well being.

Public
—•Expert•7 min
Does going out when it is chilly really make you catch a cold?

Does going out when it is chilly really make you catch a cold?

Public
—•HealthScience•Intermediate•1 min
Critical thinking and cognitive bias: complex questions

Critical thinking and cognitive bias: complex questions

Public
—•Intermediate•4 min
Why AI Needs to Stop Learning

Why AI Needs to Stop Learning

Public
—•Technology•Intermediate•11 min
Orbital Compute for AI — Reality Check

Orbital Compute for AI — Reality Check

Public
—•TechnologyBusiness•Intermediate•8 min
The Rosenthal (Pygmalion) Effect: When Expectations Change Outcomes

The Rosenthal (Pygmalion) Effect: When Expectations Change Outcomes

Public
—•ScienceCulture•Intermediate•4 min
Meta’s $100bn AI Gamble: Can Zuckerberg’s “Personal Superintelligence” Save the Company?

Meta’s $100bn AI Gamble: Can Zuckerberg’s “Personal Superintelligence” Save the Company?

Public
—•BusinessTechnology•Intermediate•10 min
Epstein money

Epstein money

Public
—•BusinessPolitics•Intermediate•6 min
The surprising ‘illusion’ behind AI chatbots.

The surprising ‘illusion’ behind AI chatbots.

Public
—•Technology•Intermediate•3 min
Tragic history of the Radium Girls

Tragic history of the Radium Girls

Public
—•HistoryPoliticsBusiness•Intermediate•4 min
4 Ways AI Is Killing the User Interface As We Know It

4 Ways AI Is Killing the User Interface As We Know It

Public
—•TechnologyBusiness•Intermediate•3 min
Andouillette: The Sausage That Separates the French from the Faint-Hearted

Andouillette: The Sausage That Separates the French from the Faint-Hearted

Public
—•FoodCulture•Beginner•56 sec
A Turning Point for European Agriculture: Brussels Backs Lighter-Touch Gene Editing

A Turning Point for European Agriculture: Brussels Backs Lighter-Touch Gene Editing

Public
—•BusinessFoodEnvironment•Intermediate•3 min
A First Glimpse of Non-Viral CRISPR Therapy Working in the Brain

A First Glimpse of Non-Viral CRISPR Therapy Working in the Brain

Public
—•ScienceHealth•Intermediate•4 min
The rise of the China's Biotech industry

The rise of the China's Biotech industry

Public
—•BusinessScience•Intermediate•4 min
5 Things You Didn't Know About the Legendary Arecibo Telescope

5 Things You Didn't Know About the Legendary Arecibo Telescope

Public
—•TechnologyHistory•Intermediate•4 min
Tell the story of Larry Walters’ (aka Lawnchair Larry) homebrew balloon flight.

Tell the story of Larry Walters’ (aka Lawnchair Larry) homebrew balloon flight.

Public
—•HistoryFun•Intermediate•3 min
What really happened at the Battle of Ramree Island (1945)?

What really happened at the Battle of Ramree Island (1945)?

Public
—•History•Intermediate•4 min
Why is 'Black Friday' a thing in the UK? How did that come about?

Why is 'Black Friday' a thing in the UK? How did that come about?

Public
—•CultureBusiness•Intermediate•5 min
CRISPR Lowers Cholesterol by 50–60%: What the CTX310 Trial Really Showed

CRISPR Lowers Cholesterol by 50–60%: What the CTX310 Trial Really Showed

Public
—•ScienceHealthTechnologyBusiness•Intermediate•4 min
The Power of Combinations: How "Design of Experiments" Supercharges Biotech Discovery

The Power of Combinations: How "Design of Experiments" Supercharges Biotech Discovery

Public
—•Science•Intermediate•4 min
Ice is a mineral, and water is lava

Ice is a mineral, and water is lava

Public
—•Science•Beginner•3 min
The surprising history of Thanksgiving.

The surprising history of Thanksgiving.

Public
—•History•Beginner•3 min
The promise of xenotransplantation: gene-edited porcine kidneys for human transplantation.

The promise of xenotransplantation: gene-edited porcine kidneys for human transplantation.

Public
—•HealthScience•Expert•4 min
The New Politics of Autism

The New Politics of Autism

Public
—•Health•Intermediate•15 min
AI news update: Waymo, LLM agentic task benchmarks, etc - 22 Nov 2025

AI news update: Waymo, LLM agentic task benchmarks, etc - 22 Nov 2025

Public
—•Technology•Intermediate•8 min
CRISPR vs cholesterol - can gene editing prevent heart disease?

CRISPR vs cholesterol - can gene editing prevent heart disease?

Public
—•Health•Intermediate•2 min
A Stress Test for In-Vivo CRISPR: Inside Intellia's MAGNITUDE Safety Pause

A Stress Test for In-Vivo CRISPR: Inside Intellia's MAGNITUDE Safety Pause

Public
—•Health•Intermediate•4 min
Overview of the field of AI, current capabilities and uses of AI, and future outlook

Overview of the field of AI, current capabilities and uses of AI, and future outlook

Public
—•Intermediate•6 min
The Cult of AGI

The Cult of AGI

Public
—•Technology•Intermediate•4 min
The story of JD Vance’s venture fund Narya

The story of JD Vance’s venture fund Narya

Public
—•BusinessPolitics•Intermediate•4 min
What is a quantum computing?

What is a quantum computing?

Public
—•Intermediate•1 min
How Close Are We to Real-World Quantum Computing?

How Close Are We to Real-World Quantum Computing?

Public
—•Intermediate•3 min
CRISPR: The Tool That Quietly Reshaped Modern Biology

CRISPR: The Tool That Quietly Reshaped Modern Biology

Public
—•HealthTechnologyScience•Intermediate•4 min
CRISPR: Intro

CRISPR: Intro

Public
—•Science•Intermediate•1 min
In the context of CRISPR/Ca9, what is the role of PAM and how was that understood prior to Charpentier/Doudna’s seminal Science paper in 2012?

In the context of CRISPR/Ca9, what is the role of PAM and how was that understood prior to Charpentier/Doudna’s seminal Science paper in 2012?

Public
—•Expert•7 min
The Monty Hall Paradox: Beating Your Own Intuition

The Monty Hall Paradox: Beating Your Own Intuition

Public
—•Fun•Intermediate•3 min
What are the most promising candidates for finding life beyond the Earth in our solar system?

What are the most promising candidates for finding life beyond the Earth in our solar system?

Public
—•Science•Intermediate•7 min
Did the Vikings ever settle in North America? What is the evidence? How far south did they get?

Did the Vikings ever settle in North America? What is the evidence? How far south did they get?

Public
—•History•Intermediate•6 min
What happened to the Viking settlements in Greenland?

What happened to the Viking settlements in Greenland?

Public
—•History•Intermediate•4 min
Could Sam Altman end up in jail?

Could Sam Altman end up in jail?

Public
—•NewsTechnology•Intermediate•4 min
In AI, what’s a “transformer” and how do they work?

In AI, what’s a “transformer” and how do they work?

Public
—•Technology•Intermediate•8 min
Why might superhuman AI kill everyone?

Why might superhuman AI kill everyone?

Public
—•Technology•Intermediate•6 min
Hilbert’s paradox of the grand hotel

Hilbert’s paradox of the grand hotel

Public
—•Fun•Intermediate•4 min
Mistake in land law (English common law): using Nram v Evans and drawing upon relevant case law. Assess how mistake has been interpreted in case law to date and explain its still fit for purpose.

Mistake in land law (English common law): using Nram v Evans and drawing upon relevant case law. Assess how mistake has been interpreted in case law to date and explain its still fit for purpose.

Public
—•Politics•Expert•9 min
The day humans almost destroyed the world by mistake

The day humans almost destroyed the world by mistake

Public
—•History•Beginner•3 min
How CRISPR is changing what we eat.

How CRISPR is changing what we eat.

Public
—•Health•Intermediate•4 min
What makes AI sound human?

What makes AI sound human?

Public
—•Technology•Intermediate•4 min
Could we ever live on Venus?

Could we ever live on Venus?

Public
—•Beginner•1 min
A guide to performance management

A guide to performance management

Public
—•Business•Intermediate•3 min
How your microbiome shapes your mind, mood, and immune system

How your microbiome shapes your mind, mood, and immune system

Public
—•HealthScience•Intermediate•7 min
What is QAnon?

What is QAnon?

Public
—•Politics•Intermediate•4 min
Tipping Point - When the Climate Flips Overnight

Tipping Point - When the Climate Flips Overnight

Public
—•Environment•Intermediate•7 min
The hidden world of synthetic biology: designing life from scratch

The hidden world of synthetic biology: designing life from scratch

Public
—•ScienceTechnology•Intermediate•8 min
The CRISPR decade: how gene editing moved from miracle to mainstream

The CRISPR decade: how gene editing moved from miracle to mainstream

Public
—•ScienceTechnology•Intermediate•8 min
What is the Fermi paradox, and is it still valid?

What is the Fermi paradox, and is it still valid?

Public
—•Science•Intermediate•5 min
What is the probability of existence of intelligent extraterrestrial life?

What is the probability of existence of intelligent extraterrestrial life?

Public
—•Science•Intermediate•8 min
Is microwave cooking nuking all the ingredients?

Is microwave cooking nuking all the ingredients?

Public
—•FoodHealth•Intermediate•3 min
OMERs pension investor

OMERs pension investor

Public
—•Business•Intermediate•3 min
5654 and Co comms agency - capabilities and approach

5654 and Co comms agency - capabilities and approach

Public
—•Business•Intermediate•4 min
Will humanity ever go extinct, statistically speaking?

Will humanity ever go extinct, statistically speaking?

Public
—•Science•Expert•7 min
Why are conspiracy theories so sticky?

Why are conspiracy theories so sticky?

Public
—•Culture•Intermediate•5 min
Could we ever grow food on Mars?

Could we ever grow food on Mars?

Public
—•TechnologyScience•Intermediate•4 min
What would happen if the Earth stopped spinning?

What would happen if the Earth stopped spinning?

Public
—•Science•Intermediate•5 min
Brain–computer interfaces: where thoughts meet machines

Brain–computer interfaces: where thoughts meet machines

Public
—•TechnologyHealth•Expert•7 min
Why ancient Rome had better concrete than us.

Why ancient Rome had better concrete than us.

Public
—•HistoryTechnology•Intermediate•3 min
Why pirates wore eye patches

Why pirates wore eye patches

Public
—•History•Beginner•53 sec
Why bananas are radioactive

Why bananas are radioactive

Public
—•HealthFoodScience•Intermediate•1 min
Can CRISPR cure Huntington’s Disease?

Can CRISPR cure Huntington’s Disease?

Public
—•HealthScience•Intermediate•6 min